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Scientist Preclinical Immunology

Vacaturenummer: A2200100
Janssen Vaccines & Prevention - Leiden (Nederland)

For our client, Janssen Vaccines & Prevention, we are looking for a Scientist Preclinical Immunology .


  • Ph.D.
  • Mouse models
  • Immunology
  • Bacteria

The Bacterial Vaccines department is looking for a Scientist to join the Preclinical Immunology team. In this role, you will support the Bacterial Vaccines project teams by working on the development of vaccines against E. coli and S. aureus infection. You will evaluate the immunogenicity and efficacy of vaccine candidates in in vitro and in vivo models. You will write study plans and study reports, perform data analysis and interpretation and will prepare presentations to internal and, occasionally, external partners. You will work in close collaboration with other (assistant/associate) scientists, co-ordinate lab activities, and supervise technicians in your day-to-day activities.

Who we're looking for
The ideal candidate has a Ph.D. in biological/medical sciences with a strong immunology/bacteriology background. You are certified to work with animal models (art. 9 or comparable) and you have hands-on experience with in vivo mouse models. This includes general mouse handling, performing immunisations, and blood and tissue collections. Experience with designing and evaluation of pre-clinical in vivo models is a plus.
In addition, you should have knowledge of immunological techniques such as ELISA, killing assays, B- and T-cell ELISpot, T cell proliferation assays, cytokine release assays, multiparameter flow cytometry and cell culturing.
Are you the pro-active and problem solving team player we are looking for?

Company profile
Janssen Vaccines & Prevention B.V. is part of Johnson & Johnson, one of the biggest and most respected health care companies in the world. They are dedicated to bringing meaningful innovation to global health. Their teams focus on the discovery, development, manufacturing, and marketing of novel vaccines to prevent some of the most devastating and complex infectious diseases. These range from respiratory infections like respiratory syncytial virus (RSV) to human immunodeficiency virus (HIV) and pathogens of global concern, such as Ebola and COVID-19.
In this organisation, entrepreneurial people are working in a dynamic culture in which innovation and a 'can do' state of mind are of crucial importance. They are continuously looking for enthusiastic, talented people who have the ambition to develop themselves and can be of value to Janssen. The offices of Janssen Vaccines & Prevention are located in Leiden, The Netherlands.

The Bacterial Vaccines department is working on the discovery- and early development of novel vaccines against bacterial infectious diseases. It strives to address unmet medical needs, such as bacteremia (sepsis) and nosocomial infections. Within this department, the Immunology group evaluates the immunogenicity and efficacy of potential vaccine candidates against several bacterial diseases in animal models. Assays to examine humoral and cellular immune responses are used to generate appropriate scientific data to show proof of concept and thereby enabling vaccine candidates to progress towards clinical phase evaluation. Currently, a Phase 3 clinical study is ongoing with a multivalent ExPEC vaccine, and another vaccine candidate is moving into development and Phase 1 studies are planned.

Additional vacancy information
Contract:Temporary contract with CLS Services
Employment terms:Salary: >4300
Days of leave: 36
See here our other employment terms for this vacancy
Project for at least 1 year
Publication date:25-7-2022
Location:View location with Google Maps
Contactperson:Claudia Erwich-Faaij
+31 (0)88 22 77 555

CLS Services is a leading professional recruitment agency, specialised in the recruitment and career coaching of people with a background in chemistry & life sciences.